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Monitor volume status and renal function periodically. The antihypertensive and diuretic effects of torsemide can be reduced by NSAIDs. In patients with decompensated congestive heart failure, hepatic and renal clearance are both reduced, probably because of hepatic congestion and decreased renal plasma flow, respectively. The renal clearance of torsemide is lower in elderly subjects as compared to younger adults, which is related to  the decline in renal function that commonly occurs with aging. Ninety-six patients were treated in this study; 6/32 treated with torsemide experienced seizures, 6/32 treated with comparably high doses of furosemide experienced seizures, and 1/32 treated with placebo experienced a seizure. Torsemide oral tablet (Demadex) is used to treat high blood pressure and edema. No data are available to suggest physiological maneuvers (e.g., maneuvers to change the pH of the urine) that might accelerate elimination of torsemide and its metabolites. Fetal and maternal toxicity (decrease in average body weight, increase in fetal resorption and delayed fetal ossification) occurred in rabbits and rats given doses 4 (rabbits) and 5 (rats) times larger. With chronic administration, however, daily sodium loss comes into balance with dietary sodium intake. Potassium Chloride Injection Description This Potassium Chloride Injection, is a sterile, nonpyrogenic, highly concentrated, ready-to-use, solution of Potassium Chloride, USP in Water for Injection, USP for electrolyte replenishment in a single dose container for intravenous administration. DYTOR intravenous (IV) injection should be administered either slowly as a bolus over a period of 2 minutes or administered as a continuous IV infusion. Further, in severe cases of edema, where a greater amount of loop diuretic is desired, the patient could be shifted to four tablets of DYTOR PLUS 20 . The usual initial dose is 10 mg or 20 mg of once-daily oral or IV torsemide. Includes indications, proper use, special instructions, precautions, and possible side effects. Diuretics can suppress lactation. If the diuretic response is inadequate, the dose should be titrated upward by approximately doubling until the desired diuretic response is obtained. Torasemide, also known as torsemide, is a diuretic medication used to treat fluid overload due to heart failure, kidney disease, and liver disease and high blood pressure. 2003 Dec;5(6):793-801. ! There are no available data on use of torsemide in pregnant women and the risk of major birth defects or miscarriage. DYTOR tablets may be given at any time in relation to a meal, as convenient. pressure within 4 to 6 weeks, the dose may be increased to 10 mg daily. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Dytor 10 MG Injection is used for Edema (Swelling), Hypertension etc. Safety and effectiveness in pediatric patients have not been established. In hypertensive patients who received 10 mg of torsemide daily for 6 weeks, the mean increase in blood urea nitrogen was 1.8 mg/dL. Administration of another loop diuretic to  premature infants has been associated with the precipitation of nephrocalcinosis/nephrolithiasis. Edema associated with Chronic Renal Failure. Partial inhibition of the natriuretic effect of torsemide by concomitant administration of indomethacin has been demonstrated for torsemide under conditions of dietary sodium restriction (50 mEq/day) but not in the presence of normal sodium intake (150 mEq/day). Excessive diuresis may cause potentially symptomatic dehydration, blood volume reduction and hypotension and worsening renal function, including acute renal failure particularly in salt-depleted patients or those taking renin-angiotensin aldosterone inhibitors. DYTOR is contraindicated in patients with. All patients should be cautioned that inadequate fluid intake, excessive perspiration, diarrhea, or vomiting can lead to an excessive fall in blood pressure, with the same consequences of lightheadedness and possible syncope, Non-Steroidal Anti-inflammatory Drugs (NSAID): Advise patients to discuss with their physician before taking NSAID medications concomitantly, Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai, Maharashtra, INDIA, Currently there are no topics under this speciality. The patients should be told that if syncope occurs, DYTOR should be discontinued until the physician has been consulted. IV twice a day, Injection optineuron 1 ample in normal saline IV once a day, Injection Lupinox 0.4cc subcutaneous twice a day, injection Piptaz 4.5 gm in 100 ml normal saline IV trice a day, injection Febrinil 75 mg once daily in Special dosage adjustment in the elderly is not necessary. The usual initial dose is 5 mg daily. In pre-approval studies, torsemide has been evaluated for safety in approximately 4000 subjects; over 800 of these subjects received torsemide for at least 6 months, and over 380 were treated for more than 1 year. DYTOR intravenous (IV) injection should be administered either slowly as a bolus over a period of 2 minutes or administered as a continuous IV infusion. Treating Functional Constipation in Children: PEG 3350 vs... Overuse of Short Acting β2-Agonists in Asthma in European... Edema associated with congestive heart failure, renal disease, or hepatic disease. However, total plasma clearance and elimination half-life remain unchanged. amlodipine, lisinopril, metoprolol, losartan, furosemide, hydrochlorothiazide, carvedilol, spironolactone, Lasix, torsemide. On a body-weight basis, these doses are 27 to 96 times a human dose of 20 mg; on a body-surface-area basis, they are 5 to 8 times this dose. In United States placebo-controlled trials excessive urination occurred in 6.7% of patients compared with 2.2% of patients receiving placebo.

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